Prof. Dr. Dong-Sheng Guo
College of Chemistry, Nankai University
GUO group focuses our research interest on supramolecular biomedical materials.
Supramolecular chemistry focuses on intermolecular non-covalent interactions
and studies the recognition and assembly behavior between two or more
molecules. We apply the fundamental principles of supramolecular chemistry to
create enhanced diagnostics, therapeutics and theranostics.
Address：College of Chemistry, Nankai University, 94 Weijin Road,
The GUO group focuses the research interest on supramolecular biomedical materials. Supramolecular chemistry refers to the chemistry based on intermolecular non-covalent interactions and studies the recognition and assembly behavior between two or more molecules. We apply the fundamental principles of supramolecular chemistry to create enhanced diagnostics, therapeutics and theranostics. The central theme of our group is the macrocyclic receptor calixarene, which imparts intriguing recognition and assembly features after subtle modifications. Research in the group involves an interdisciplinary mix of organic synthesis, supramolecular physical chemistry, bio-sensing/imaging, and nanomedicine.
Angew. Chem. Int. Ed., 2017, 56, 15742–15745
Phosphorylation‐Responsive Membrane Transport of Peptides Shu Peng, Andrea Barba-Bon, Yu-Chen Pan, Werner M. Nau, Dong-Sheng Guo,* and Andreas Hennig*
J. Am. Chem. Soc., 2018, 140, 4945–4953
Biomarker Displacement Activation: a General Host-Guest Strategy for Targeted Phototheranostics in Vivo
Jie Gao, Jun Li, Wen-Chao Geng, Fang-Yuan Chen,Xingchen Duan, Zhe Zheng, Dan Ding* and Dong-Sheng Guo*
Nat. Chem., 2019, 11, 86–93
Heteromultivalent peptide recognition by co-assembly of cyclodextrin and calixarene amphiphiles enables inhibition of amyloid fibrillation
Zhe Xu, Shaorui Jia, Wei Wang, Zhi Yuan, Bart Jan Ravoo & Dong-Sheng Guo
Chem. Sci., 2018, 9, 2087-2091
Ultrasensitive and specific fluorescence detection of a cancer biomarker via nanomolar binding to a guanidinium-modified calixarene
Zhe Zheng, Wen-Chao Geng, Jie Gao, Yu-Ying Wang, Hongwei Sun and Dong-Sheng Guo*